Does Flexeril Show Up on a DOT Drug Test?

Flexeril (cyclobenzaprine) is a widely prescribed muscle relaxer used to treat muscle spasms and injuries. Many commercial drivers are concerned about whether taking Flexeril could cause a failed DOT drug test.

The answer is no, Flexeril does not show up on a DOT drug test.

What DOT Drug Tests Include

DOT drug testing follows strict federal guidelines and screens for only five drug categories:

  • Marijuana
  • Cocaine
  • Amphetamines
  • Opiates
  • PCP

Flexeril is not part of these categories.

Why Flexeril Is Not Detected

Flexeril works as a central nervous system muscle relaxant, but it is not a controlled substance in the categories tested by DOT programs.

Because of this:

  • It does not produce metabolites associated with tested drugs
  • It does not trigger positive results in standard DOT testing

Can Flexeril Cause a False Positive?

False positives are rare but possible with some medications.

In the case of Flexeril, false positives are uncommon. Even if a screening test reacts, confirmation testing will identify the correct substance.

Safety Considerations for CDL Drivers

While Flexeril does not affect drug testing results, it can impact driving ability.

Common side effects include:

  • Drowsiness
  • Dizziness
  • Slowed reaction time

These effects can be dangerous for commercial drivers.

DOT Medical Certification

During a DOT physical exam, the medical examiner may evaluate:

  • Why Flexeril is prescribed
  • Frequency of use
  • Side effects

Drivers may need to provide documentation confirming safe use.

Final Thoughts

Flexeril will not cause a failed DOT drug test, but it may still affect a driver’s ability to safely operate a vehicle.

Key points include:

  • It is not included in DOT drug testing panels
  • It does not typically cause false positives
  • Side effects are the primary concern

Drivers should always prioritize safety when taking any medication.